Airlines that successfully undergo an IATA Standard Safety Assessment (ISSA) are placed on the ISSA Registry for a period of 24 months. See the ISSA Audit scope and eligibility and the audit organizations accredited to conduct ISSA audits.
List of airlines currently on the ISSA registry:
11 ISSA registered airlines found
| Airline name | Region | Country / Territory | Registration Expiry |
| Amaszonas Linea Aerea | The Americas | Bolivia | 13 July 2021 |
| Amaszonas Uruguay | The Americas | Uruguay | 16 August 2021 |
| ASTA Linhas Aéreas | The Americas | Brazil | 25 September 2021 |
| Compagnie Aérienne Inter Régionale Express (CAIRE) | The Americas | Guadeloupe | 28 February 2021 |
| RIMA Rio Madeira Aerotaxi | The Americas | Brazil | 28 September 2021 |
| Safarilink Aviation Limited | Africa & Middle East | Kenya | 23 August 2020 |
| SANSA, Servicios Aéreos Nacionales S.A. | The Americas | Costa Rica | 6 December 2021 |
| Tara Air Pvt. Ltd. | Asia Pacific | Nepal | 17 May 2020 |
| Tropic Air Limited | The Americas | Belize | 15 February 2022 |
| TwoFlex | The Americas | Brazil | 24 July 2021 |