Airlines that successfully undergo an IATA Standard Safety Assessment (ISSA) are placed on the ISSA Registry for a period of 24 months. See the ISSA Audit scope and eligibility and the audit organizations accredited to conduct ISSA audits.
List of airlines currently on the ISSA registry:
12 ISSA registered airlines found
| Airline name | Region | Country / Territory | Registration Expiry | ICAO Code | IATA Code |
| Aerosul Linhas Aereas Ltda | The Americas | Brazil | 12 January 2024 | ASO | |
| ATA- Aerotáxi Abaete LTDA | The Americas | Brazil | 20 October 2024 | ABJ | |
| Azul Conecta | The Americas | Brazil | 28 May 2023 | OWT | 2F |
| Coastal Travels Limited | Africa & Middle East | Tanzania, United Republic of | 4 March 2025 | CSV | CQ |
| RIMA Rio Madeira Aerotaxi | The Americas | Brazil | 28 July 2023 | RIM | |
| SANSA, Servicios Aéreos Nacionales S.A. | The Americas | Costa Rica | 5 December 2023 | LRS | RZ |
| ST BARTH COMMUTER | The Americas | France | 3 November 2024 | SBU | PV |
| Star Up S.A. | The Americas | Peru | 15 December 2023 | SRU | |
| TEZ JET AIRLINE | Europe | Kyrgyzstan | 26 April 2024 | TEZ | |
| Trans Guyana Airways Limited | The Americas | Guyana | 1 April 2025 | TGY |