The IATA Operational Safety Audit (IOSA) is the benchmark for global safety management in airlines. All IATA members are registered and must remain registered in order to maintain IATA membership. See the applicability of IOSA standards and recommended practices (ISARPs).
Current list of IOSA registered airlines:
Found 412 operators
| Name | IATA code | ICAO code | Country / Territory | Region | Expiry Date |
| ABX Air Inc | GB | ABX | United States | The Americas | 26 October 2023 |
| ACT Airlines | 9T | RUN | Türkiye | Europe | 27 November 2024 |
| Aegean Airlines SA | A3 | AEE | Greece | Europe | 10 June 2025 |
| Aer Lingus Limited | EI | EIN | Ireland | Europe | 21 October 2023 |
| Aero Republica SA | P5 | RPB | Colombia | The Americas | 7 December 2024 |
| Aerolineas Argentinas SA | AR | ARG | Argentina | The Americas | 2 November 2024 |
| Aeromexico | AM | AMX | Mexico | The Americas | 13 November 2024 |
| Aeromexico Connect | 5D | SLI | Mexico | The Americas | 1 July 2025 |
| Aerotransportes Mas de Carga SA de CV MasAir | M7 | MAA | Mexico | The Americas | 13 January 2024 |
| Africa World Airlines | AW | AFW | Ghana | Africa & Middle East | 1 May 2024 |